eSyM Manuscripts
Manuscripts
2026
"Longitudinal Patterns of Symptoms in Patients Undergoing Chemotherapy: A Secondary Analysis of a Cluster Randomized Clinical Trial"
Paudel R, Wright AA, Cronin CM, Uno H, Barrett F, Brooks GA, Hazard-Jenkins HW, Wong SL, Dizon DS, Bian JJ, Osarogiagbon RU, Schrag D, Hassett MJ. Longitudinal Patterns of Symptoms in Patients Undergoing Chemotherapy: A Secondary Analysis of a Cluster Randomized Clinical Trial. JAMA Network Open. 2026 Apr 1; 9 (4): e264996. doi: 10.1001/jamanetworkopen.2026.4996. PMID: 41941188; PMCID: PMC13054620.
Citation:
2025
"Patient and staff experiences with an EHR-Integrated Symptom Management Program (eSyM) in oncology"
Cronin CM, Barrett F, Dias S, Paudel R, Osarogiagbon RU, Schrag D, Wong SL, Dizon DS, Bian JJ, Hazard-Jenkins HW , Brooks GA, Revette A, Hassett MJ. Patient and staff experiences with an EHR-Integrated Symptom Management Program (eSyM) in oncology. Supportive Care in Cancer. 2025 Dec 24; 34 (1): 54. doi: 10.1007/s00520-025-10248-8. PMID: 41442064; PMCID: PMC12738592.
Citation:
"Self-reported overall well-being and physical function among chemotherapy and surgery patients across six institutions"
Hassett MJ, Cronin CM, Tramontano AC, Wong SL, Uno H, Paudel R, Bian JJ, Dizon DS, Hannah Hazard-Jenkins H, Osarogiagbon RU, Schrag D. Self-reported overall well-being and physical function among chemotherapy and surgery patients across six institutions. Cancer. 2025 Dec 1; 131 (23). doi: 10.1002/cncr.70185. PMID: 41307896; PMCID: PMC12659802.
Citation:
"Does Electronic Symptom Monitoring Improve Symptom Burden and Self-Efficacy Among Chemotherapy and Surgery Patients Across Six Cancer Centers?"
Bian JJ, Dias SL, Wright PA, Tramontano AC, Cronin CM, Osarogiagbon RU,
Schrag D, Wong SL, Dizon DS, Hazard-Jenkins H, Hassett MJ. Does Electronic Symptom Monitoring Improve Symptom Burden and Self-Efficacy Among Chemotherapy and Surgery Patients Across Six Cancer Centers? JCO Oncology Practice. 2025 Nov 13. doi: 10.1200/OP-25-00306. PMID: 41232046; PMCID: PMC12712840.
Citation:
"Staff Perspectives on Normalizing and Sustaining Electronic Patient-Reported Outcomes Monitoring at Six US Health Systems"
Paudel R, Uno H, Cronin C, Dizon DS, Hazard-Jenkins H, Bian J, Osarogiagbon RU, Wong SL,
Schrag D, Hassett MJ. Staff Perspectives on Normalizing and Sustaining Electronic Patient-Reported Outcomes Monitoring at Six US Health Systems. JCO Oncology Practice. 2025 Sep 5. doi: 10.1200/OP-25-00049. PMID: 40911809.
Citation:
"Using Quality Improvement and Implementation Science to Identify Strategies That Foster Electronic Patient-Reported Outcome Submissions"
Doolin JW, Dias SL, Cronin C, Dizon DS, Hazard-Jenkins HW, Bian JJ, Wong SL, Schrag D, Paudel R, Osarogiagbon RU, Hassett MJ. Using Quality Improvement and Implementation Science to Identify Strategies That Foster Electronic Patient-Reported Outcome Submissions. Journal for Healthcare Quality. 2025 Jul 24; 47 (3). doi: 10.1097/JHQ.0000000000000478. PMID: 40705678; PMCID: PMC12313094
Citation:
"The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation"
Beqari J., Hurd J., Tramontano AC., Cronin C., Potter A., Wong S., Schrag D., Dizon DS., Bian J., Osarogiagbon RU., Hazard-Jenkins H., Phillips JD., Abbas AE., Warikoo IM., Anderson M., Seastedt KP., Lanuti M., Colson Y., Wright CD., Hassett MJ., & Yang C. The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation. JTCVS Open. 2025. doi: 10.1016/j.xjon.2025.02.010.
Citation:
"Perceptions of an Electronic Patient Symptom Reporting Tool by Clinicians"
Citation:
Mallow J., Bailey A., Tasker L., Hazard H., Hassett M., Cronin C., Paudel R., Bian J., Dizon DS., Osarogiagbon RU., Schrag D., & Wong S. Perceptions of an Electronic Patient Symptom Reporting Tool by Clinicians. Computers, Informatics, Nursing. 2025 Apr. doi: 10.1097/CIN.0000000000001313.
2024
"Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers"
Citation:
Hassett M.J., Dias S., Cronin C., Schrag D., McCleary N., Simpson J., Poirier-Shelton T., Bian J., Reich J., Dizon D., Begnoche M., Jenkins H.H., Tasker L., Wong S., Pearson L., Paudel R., Osarogiagbon R.U. Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers. BMC Health Services Research. 2024 Nov; 24(1). doi: 10.1186/s12913-024-11536-5. PMID: 39533260; PMCID: PMC11558981.
"Use of Patient-Reported Outcomes in Risk Prediction Model Development to Support Cancer Care Delivery: A Scoping Review"
Citation:
Paudel R, Dias S, Wade CG, Cronin C, Hassett MJ. Use of Patient-Reported Outcomes in Risk Prediction Model Development to Support Cancer Care Delivery: A Scoping Review. JCO Clin Cancer Inform. 2024 Nov;8:e2400145. doi: 10.1200/CCI-24-00145. Epub 2024 Nov 1. PMID: 39486014; PMCID: PMC11534280
"Effects of a change in recall period on reporting severe symptoms: an analysis of a pragmatic multisite trial"
Citation:
"Electronic Patient-Reported Outcomes in Oncology: Lessons from Six Cancer Centers"
Citation:
Cronin C, Barrett F, Dias S, Wong S, Pearson L, Hazard-Jenkins H, Bian J, Dizon D, Osarogiagbon R, Schrag D, Hassett MJ. Electronic Patient-Reported Outcomes in Oncology: Lessons from Six Cancer Centers. NEJM Catalyst. 2024 Jan;5. doi: 10.1056/CAT.23.0331. Epub 2024 Jan 17.
2023
"Assessing Patient Readiness for an Electronic Patient-Reported Outcome-Based Symptom Management Intervention in a Multisite Study"
Citation:
Paudel R, Tramontano AC, Cronin C, Wong SL, Dizon DS, Hazard-Jenkins H, Bian J, Osarogiagbon R, Schrag D, Hassett MJ. Assessing Patient Readiness for an Electronic Patient-Reported Outcome-Based Symptom Management Intervention in a Multisite Study. JCO Oncol Prac. 2023 Nov;20. doi: 10.1200/OP.23.00339. Epub 2023 Nov 27.
2022
"Implementation of patient-reported outcomes for symptom management in oncology practice through the SIMPRO research consortium: a protocol for a pragmatic type II hybrid effectiveness-implementation multi-center cluster-randomized stepped wedge trial"
Citation:
Hassett, M. J., Wong, S., Osarogiagbon, R. U., Bian, J., Dizon, D. S., Jenkins, H. H., Uno, H., Cronin, C., Schrag, D., & SIMPRO Co-Investigators (2022). Implementation of patient-reported outcomes for symptom management in oncology practice through the SIMPRO research consortium: a protocol for a pragmatic type II hybrid effectiveness-implementation multi-center cluster-randomized stepped wedge trial. Trials, 23(1), 506. https://doi.org/10.1186/s13063-022-06435-1
"eSyM: An Electronic Health Record–Integrated Patient-Reported Outcomes–Based Cancer Symptom Management Program Used by Six Diverse Health Systems"
Citation:
Hassett MJ, Cronin C, Tsou TC, Wedge J, Bian J, Dizon DS, Hazard-Jenkins H, Osarogiagbon RU, Wong S, Basch E, Austin T, McCleary N, Schrag D. eSyM: An Electronic Health Record-Integrated Patient-Reported Outcomes-Based Cancer Symptom Management Program Used by Six Diverse Health Systems. JCO Clin Cancer Inform. 2022 Jan;6:e2100137. doi: 10.1200/CCI.21.00137. Epub 2022 Jan 5.
2019
"Patient-reported outcomes in surgical oncology: An overview of instruments and scores"
Citation:
Phillips JD, Wong SL. Patient-reported outcomes in surgical oncology: An overview of instruments and scores. Ann Surg Oncol. 2020 Jan;27(1):45-53. doi: 10.1245/s10434-019-07752-7. Epub 2019 Aug 28.
"Translation of patient-reported outcomes in oncology clinical trials to everyday practice"
Citation:
Ivatury SJ, Hazard-Jenkins HW, Brooks GA, McCleary NJ, Wong SL, Schrag D. Translation of Patient-Reported Outcomes in Oncology Clinical Trials to Everyday Practice. Ann Surg Oncol. 2020 Jan;27(1):65-72. doi: 10.1245/s10434-019-07749-2. Epub 2019 Aug 26.